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Results PDT combined with chitosan showed maximum bactericidal effect followed by PDT for 40 seconds and chitosan groups (P less then 0.05). PDT for 30 seconds showed a minimum bactericidal effect (P less then 0.05). All pairwise comparisons revealed significant differences (P less then 0.001). Conclusion Chitosan and PDT alone can be used to decrease the S. mutans count. However, their combined use has a greater bactericidal effect on S. mutans .Introduction Darier disease (DD) is a chronic disease with high morbidity and limited treatme
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