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The consequences of traumatic brain injury (TBI) are highly variable, often including both cognitive and psychiatric difficulties, and a greater probability of developing dementia over the long term. The UK's Afghanistan campaign was marked by a high incidence of complex polytrauma, including TBI, significantly increasing occupational risk for military personnel. The ADVANCE-TBI substudy will characterize the trends, links, and lasting impacts of traumatic brain injury (TBI) among participants in the pre-existing ADVANCE cohort. The ADVANCE cohort includ