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Ventilated neonates with hypoxemic respiratory failure (HRF) may show a ventilation-perfusion (V/Q) mismatch. To evaluate the difference between the Bohr (V ) and Enghoff (V ) dead spaces in infants by using volumetric capnography based on ventilator graphics and capnograms. This study enrolled 46 ventilated infants (mean birth weight, 2239 ± 640 g; mean gestational age, 35.5 ± 3.3 weeks). We performed volumetric capnography and calculated V and V when arterial blood sampling was necessary for treatment. According to the oxygenation i