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2 and 7.4, respectively in contrast to those of physical mixture (PhyMix) (∼35% and ∼10%) and pure LORX (∼17% and ∼7%) within 60 min. The and AUC for the selected cocrystal were significantly increased ( 0.05) which was 2.4 and 2.5 times, respectively, that of LORX in a single dose oral pharmacokinetic study executed in rabbits. Tablets of cocrystal were found stable at both conditions. The study indicates that cocrystallization with DMU can concomitantly improve tabletability, dissolution rate, and performance of dissolution limited drug LORX. The st
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