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Mental health care professionals are at risk of experiencing burnout. This cross-sectional study aims to investigate burnout in two settings open and closed psychiatric wards, and two professions registered nurses and social healthcare assistants in eight psychiatric wards in Denmark. A total of 114 professionals completed the Copenhagen Burnout Inventory and a demographic questionnaire. No statistically differences in burnout in professionals working in closed and open wards were found. However, we found professionals to score highest