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30 million years ago, ancestors of Old World primates lost the ability to produce α-gal. In this issue of Cell Host Microbe, Singh et al. (2021) show that the loss is associated with increased resistance to sepsis, but that this advantage comes alongside a cost of accelerated reproductive senescence.RNA expression of endogenous retroviral elements poses a threat to the genome and to cell function, which may ultimately result in disease. Recently published in Nature, Chelmicki and colleagues (2021) identify m6A mRNA methylation as
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